retatrutide clinical trials weight loss retatrutide Phase III study demonstrates 30% Retatrutide Subcutaneous Fat Loss Results:

Altered GI motility and changes in bile acid metabolism can cause loose stools, particularly during titration

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Severe or persistent diarrhea defined as more than six loose stools daily lasting beyond 48 hoursrequires clinical assessment to prevent complications and rule out alternative causes unrelated to the weight loss medication